12 week old ragdoll x Maine coons Pregnant tortoiseshell pregnant to my ragdoll Proven Blue mitted male for stud only Lottie perfect beginner cat with everything needed Remarkable Purebred ragdoll kitten Lovely Ragdoll Kittens for Sale PEDIGREE RAGDOLL KITTENS READY SOON Champion Blue Point Ragdoll GCCF Active Proven Blue Tabby Mitted Boy GCCF active available for STUD Female Pedigree Ragdoll Queen for sale Posted on iPhone 22/08/2016 Ragdoll blue bicolour boy Pure Ragdoll male kitten Ragdoll kittens readvertised due to prospective buyers change of circumstances 3 female Ragdoll cross kittens ready now ragdoll kitens only 2 left Beautiful Ragdoll Kitten for Reservation Flame point Ragdoll kitten Ragdoll Kittens Ready Now Yorkshire Area GCCF registered Ragdoll kittens ready to view Gorgeous full breed chocolate point Pedigree Aussie cat abbysiannian/ American shorthair) Ragdoll kittens for sale

Quality well bred ragdolls GCCF Registered Pedigree Ragdoll KittensWe are a small breeder of Ragdoll kittens, Miniature Goldendoodle, and Havapoo puppies. We are located in Spencerport, New York, a scenic suburb of Rochester. We are a NYS certified breeder (PD103), and you can be assured that all of the rules and regulations of proper animal rearing are followed. We are also a member of The International Cat Association (TICA), Ragdoll International (RI), the Ragdoll Fanciers Club International (RFCI), and the RFWC Ragdoll Fanciers Worldwide Club (RFWC). As a child growing up with my mother breeding Golden Retrievers, Goldendoodles, and Ragdolls, I always helped raise puppies and kittens. I have owned at least one Golden Retriever for the past twenty-five years and have helped with breeding them for the last twenty years. I recently took over Pamsdollhouse and will continue to raise our puppies and kittens with my own family.  All of our adult dogs have been health tested and are negative for hereditary diseases.

My goal is to raise happy, healthy, well-adjusted kittens from high-quality Ragdoll lines that will bring years of joy and love to their new families’ lives! Our adults have all been health tested and are negative for hereditary diseases. our kittens will melt your heart! Wisconsins’ Premier Ragdoll Cattery Welcome to Beyond the Valleyragdolls where ragdoll kittens & cats are bred for Excellence! We breed and raise high quality ragdoll cats and kittens. All our kittens are born, babied, and loved underfoot in our home. Our ragdoll cattery adheres to strict standards. All our cats and kittens are registered with TICA. Our cattery abides by the TICA Voluntary Code of Ethics. All our kittens come with a health guarantee We now have a Facebook Page! Our ragdoll cattery is located in rural Baldwin, Wisconsin. We live in a renovated 145 year old farm home. Our love of raising cats has grown over 50 years, from growing up with cats, to having cats as family members in our home, and around our farm.

Our family fell in love with the fantastic docile temperament and beautiful appearance of the ragdoll. Kelly Brook Picture Frame Duvet CoverWe decided to only breed purebred and enjoy the low maintenance, easy going, playful, and exceptionally friendly qualities. Miller Bobcat 250 Welders SaleWe are now approaching our 15th year of raising only top quality purebred ragdolls.Mountain Air Cleaners Prescott Az We treat each individual cat and kitten with unconditional love and attention. We spare no expense when it comes to health and all our cats are tested for all feline disease. Our adult cats are allowed to roam freely throughout our home and are strictly indoor cats. They eat high quality food; get a well-balanced diet, and get lots of human attention.

Kittens are fully litter trained, vaccinated and in top physical condition and well socialized before leaving our home. We are a closed cattery, meaning; no cats other than our breeding family enters our home at any time and we are off limits to visiting without a reservation. This is an insurance against any feline disease and keeps strict health control over our breeding environment. Our kittens are raised in gated nursery rooms, specially designed for kitten play and ability. This keeps our mother cats very content, and our kittens very safe and secure. We are never searching under a couch or in a closet for our kittens. Our kittens get lots of attention and socializing before leaving. They are not shy or afraid. They make the transition from our home to yours very easily. I encourage everyone to read a our testimonials, this will give you a really good idea of how much joy and happiness bringing one of our wonderful ragdoll kittens into your life will be. Also take a look at the Ragdolls with Pets page, this will end any doubts about our ragdoll kittens with companion dogs and other cats.

We also offer health supplements, grooming tools, toys, and climbers that we use and train our kittens to be used to. All items are shown in our catalog, Beyond the Valley Cat Products so please take a look! The International Cat Associationhi,i am looking for a white long haired kitten with blue eyes.i would like a male.i will k One of the polydactyl cats at the Ernest Hemingway House in Key West, Florida; this particular cat has 26 toes A polydactyl cat is a cat with a congenital physical anomaly called polydactyly (or polydactylism, also known as hyperdactyly), that causes the cat to be born with more than the usual number of toes on one or more of its paws. Cats with this genetically inherited trait are most commonly found along the East Coast of North America (in the United States and Canada) and in South West England and Wales. The true polydactyly is a congenital abnormality, genetically inherited as an autosomal dominant trait of the ZRS cis element of the Pd gene with incomplete penetrance.

Normal cats have a total of 18 toes, with five toes on each front paw and four toes on each hind paw; polydactyl cats may have as many as eight digits on their front and/or hind paws. Jake, a Canadian polydactyl cat with 28 toes, was recognised by Guinness World Records as having the highest number of toes on a cat.[2] Various combinations of anywhere from four to seven toes per paw are common.[3] Polydactyly is most commonly found on the front paws only, it is rare for a cat to have polydactyl hind paws only, and polydactyly of all four paws is even less common. The nickname "double-pawed cat" is a misnomer since there is a specific double paw condition, although this condition may be interrelated with polydactyly. Feline radial hypoplasia (see squitten) is a mimic of polydactyly and is considered a severe condition. Radial hypoplasia may cause the formation of extra jointed toes, but it is not a result of the gene normally associated with polydactyls. It thus does not cause the "mitten cat" or "thumb cat" condition where the extra toes occur separated from the normal ones just like a dewclaw, usually associated with an additional pad which makes them look like an underdeveloped foot sticking out near the base of the normal toes.

Rather, radial hypoplasia-related extra toes are immediately adjacent to the normal ones, giving the cat overly large, flat feet — colloquially known as "patty feet" or "hamburger feet". Though this looks less serious than true polydactyly (as the feet appear "normal" apart from having one or two extra toes), breeding such cats will eventually result in severely disabled offspring. Cats used in polydactyl breeding programs can be screened by x-ray for indicators of radial hypoplasia, and cats suspected to have radial hypoplasia should not be used for breeding. The condition seems to be most commonly found in cats along the East Coast of North America (in the United States and Canada) and in South West England, Wales and Kingston-upon-Hull. Polydactyl cats have been extremely popular as ship's cats. Although there is some controversy over whether the most common variant of the trait originated as a mutation in New England or was brought there from Britain, there seems to be agreement that it spread widely as a result of cats carried on ships originating in Boston, Massachusetts, and the prevalence of polydactyly among the cat population of various ports correlates with the dates when they first established trade with Boston.

[5] Contributing to the spread of polydactyl cats by this means, sailors were long known to value polydactyl cats especially for their extraordinary climbing and hunting abilities as an aid in controlling shipboard rodents. Some sailors also considered them to be extremely good luck when at sea. Genetic work studying the DNA basis of the condition however indicates that many different mutations can all lead to polydactyly[1] and since samples from the UK and USA were shown to possess different mutations it seems likely that these cats have originated multiple times independently, rather than spreading from a single origin. Nobel Prize-winning author Ernest Hemingway was a famous aficionado of polydactyl cats, after being first given a six-toed cat by a ship's captain. Upon Hemingway's death in 1961, his former home in Key West, Florida, became a museum and a home for his cats, and it currently houses approximately fifty descendants of his cats (about half of which are polydactyl).

Because of his love for these animals, polydactyl cats are sometimes referred to as "Hemingway Cats". Some sources state that these cats are rare in Europe because they were killed as witches' familiars,[5] but other sources indicate that they are quite common in southern Britain. Nicknames for polydactyl cats include "conch cats", "boxing cats", "mitten cats", "mitten-foot cats", "snowshoe cats", "thumb cats", "six-fingered cats", "Cardi-cats", and "Hemingway cats". Two specific breeds recognized by some but not all cat fancier clubs are the American Polydactyl and Maine Coon Polydactyl, and named regional populations include the Boston thumb cat, Cardi-cat, Ithacat, and Vermont snowshoe cat. American Polydactyl cats are bred as a specific cat breed, with specific physical and behavioral characteristics in addition to extra digits. The American Polydactyl is not to be confused with the pedigree Maine Coon polydactyl. The polydactyl form of the Maine Coon is being reinstated by some breeders.

A particular strain of polydactyl cats native to Ithaca, New York is known as the Ithacat. Polydactyls are very common in the Cardigan area of Wales, where they are known as "Cardi-cats." Polydactyl Red Maine Coon Kitten The database PolyTrak comprises 1800 Maine Coons in total (as of July 2014). Out of them about 1200 are polydactyl.[8] The PolyTrak database service is a repository of information for the Maine Coon polydactyl cat. Details on numbers of toes are given as well as of catteries, sires and dames. Physiological characteristics of each polydactyl individual are also stored. There is no medical injury mentioned of any polydactyl Maine Coon individual. Thus PolyTrak could help to confirm on a broad empirical base, that the polydactyl Maine Coon (Hemingway mutant) has no negative health effects at all. Preaxial polydactyly: Ectopic Shh-expression, Hemingway mutant, mouse, right forelimb Preaxial polydactyly: Maine Coon cat, Hemingway mutant, right forefoot Preaxial polydactyly, Hemingway mutant: Frequency of polydactylous digits per individual

In the case of preaxial polydactyly of the Maine Coon cat (Hemingway mutant) a mutation of the cis-regulatory element ZRS (ZPA regulator sequence) is associated. ZRS is a noncoding element, 800.000 basepairs remote to the target gene Shh. An ectopic expression of Shh is seen on the anterior side of the limb. Normally Shh is expressed in an organiser region, called the zone of polarizing activity (ZPA) on the posterior limb side. From there it diffuses anteriorly, laterally to the growth direction of the limb. In the mutant mirroring smaller ectopic expression in a new organiser region is seen on the posterior side of the limb. This ectopic expression causes cell proliferation delivering the raw material for one or more new digits. In addition to the study of genetic causes of polydactyly limb patterning models are used to simulate the congenital disorder at the limb, being able to explain the development paths of polydactyly. Polydactyly is a spontaneous complex phenotypic variation, developed in one generation.

In the concrete preaxial form of the Hemingway mutant the variation is induced by a single point mutation in a noncoding cis-regulatory element for Shh. In an extensive phenotypic variation like this, one or more complete digits at each single limb are developed including nerves, blood vessels, muscles and ligaments. The physiology of the digits can be perfect. This complex phenotypic result cannot be explained by the mutation alone. The mutation can only induce the variation. In the consequence of the mutation thousands of events, each different from the wildtype, occur on different organisation layers, i.e. expression changes of other genes, cell-cell signal exchange, cell differentiation, cell and tissue growth. The summarized small random changes on all layers build the raw material and the process steps for the generation of the plastic variation.[3] The mentioned form of polydactyly of the Hemingway mutant shows a biased variation. In a recent empirical study first the number of extra toes of 375 mutant Maine Coon cats were variable (polyphenism) and second, the number of extra toes followed a discontinuous statistical distribution.